Stages of a Cold Sore Breakout
Cold sores typically last 1-2 weeks, although in some cases they may last up to a month.¹ It’s important to understand the stages of cold sore breakouts, as knowing where you are in the process can help you – or your doctor – determine the best treatment option(s).
The most common stages of a cold sore outbreak include:¹
- Tingling: 1 day – When cold sores begin forming, sufferers commonly report feeling a tingling or burning sensation around their mouth or lips. This sensation may last a few hours, or it may last up to a full day.
- Redness: 1-2 days – During this stage of the cold sore breakout, sufferers often report the appearance of redness in the area of the outbreak. Additionally, it’s not uncommon for swelling to occur as a small bump begins to form.
- Bumps: 1-2 days – Swelling commonly gives way to the formation of a visible bump or bumps, which often occur in small clusters. These bumps commonly appear along the line where the lips meet the skin of the face, although they can also occur around the nose or on the cheeks.
- Blisters: 2-3 days – Vesicular lesions (blisters) and other small bumps begin to appear. These blisters are filled with fluid, and may burst, causing fluid to ooze from the open sore.
- Scabs: 5-7 days – The longest stage of the cold sore outbreak, the fluid and open sores created by the cold sore blisters and bumps begin to crust and scab. As these scabs shrink, it’s not uncommon for sufferers to experience painful cracking and splitting, which may lead to bleeding. Additionally, it’s not uncommon for someone suffering a cold sore outbreak to feel a severe itching and/or burning sensation during this phase.
- Redness: 1-2 days – In the final stage of the cold sore breakout, the scab falls off, leaving tender, slightly red skin behind to finish the healing process.
- WebMD (June 04, 2014). Cold Sores – Topic Overview [Skin Problems & Treatments Health Center web post]. Retrieved August 15, 2015, from http://www.webmd.com/skin-problems-and-treatments/tc/cold-sores-topic-overview
Indication & Important Safety Information
Sitavig® (acyclovir), 50mg Muco-Adhesive Buccal Tablet is indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults.
- Sitavig should not be used in patients with known hypersensitivity to acyclovir, milk protein concentrate, or other components of the product.
- Sitavig has not been studied in pregnant women or in immunocompromised patients and no interaction studies have been performed. Sitavig’s safety and efficacy have not been established in pediatric patients.
- Sitavig is a Pregnancy Category B product; therefore it should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. It is not known if Sitavig is excreted in breast milk; however, systemic absorption is minimal.
- In a controlled clinical trial Sitavig's most common side effects (greater than or equal to 1%) were: headache (3%), dizziness (1%), lethargy (1%), gingival (gum) pain (1%), aphthous stomatitis (canker sores) (1%), application site pain (1%), application site irritation (1%), erythema (1%) and rash (1%). In the same trial these side effects ranged from 0%-3% for placebo.